代表学术论文
1.Junxiang Wang, Lu Wang, Ying Xiang, Daniel Ricklin, John D. Lambris, Gang Chen (通讯作者). Using an in vitro xenoantibody-mediated complement-dependent cytotoxicity model to evaluate the complement inhibitory activity of the peptidic C3 inhibitor Cp40. Clinical Immunology 2016; 162: 37-44.
2.Lin K, Chen S, Chen G (通讯作者). Role of Memory T Cells and Perspectives for Intervention in Organ Transplantation. Front Immunol. 2015 Sep 14;6:473.
3.Junhua Li, Bo Zhao, Xuehai Zhu, Lu Wang, Huijuan Zou, Song Chen, Hui Guo, Yongle Ruan, Fang Zheng, Ying Xiang, Changsheng Ming, Feili Gong, Gang Chen (通讯作者). Blockade of extracellular HMGB1 suppresses xenoreactive B cell responses and delays acute vascular xenogeneic rejection. Am J Transplant 2015;15(8):2062-74.
4.Yongle Ruan, Lu Wang, Yue Zhao, Ying Yao, Song Chen, Junhua Li, Hui Guo, Changsheng Ming, Shi Chen, Feili Gong, Gang Chen(通讯作者). Carbon monoxide potently prevents ischemia-induced HMGB1 translocation and release and protects against lethal renal ischemia-reperfusion injury. Kidney International 2014 (86): 525-537 (SCI IF=8.54)
5.Chen G, Chen S, Chen XP. Role of complement and perspectives for intervention in transplantation. Immunobiology 2013,218:817-827.(IF=2.814 2012)
6.Chen S, Zhong S, Xiang Y, Li J-H, Guo H, Wang W-Y, Xiong Y-L, Li XC, Chen S , Chen X-P, Chen G(通讯作者).. Complement inhibition enables renal allograft accommodation and long-term engraftment in presensitized nonhuman primate. Am J Transplant 2011;11:2057-2066 (IF=6.394)
7.Li J, Chen G (Co-first author), Ye P, Wang S, Zhang K, Chen W, Stepkowski SM, Li J, Zhong S, Xia J. CCR5 Blockade in Combination with Cyclosporine Increased Cardiac Graft Survival and Generated Alternatively Activated Macrophages in Primates. J Immunol. 2011;186(6):3753-61.( IF=5.788)
8.Junhua Li, Quan Gong, Shan Zhong, Lu Wang, Hui Guo, Ying Xiang, Tomas.E. Ichim, Cong-Yi Wang, Shi Chen, Feili Gong, Gang Chen (通讯作者). Neutralization of the extracellular HMGB1 released by ischemic damaged renal cells protects against renal ischemia-reperfusion injury. Nephrology Dialysis Transplantation 2011;26:469-478 (IF= 3.396)
9.Zhuzeng Yin, Lu Wang, Ying Xiang, Yongle Ruan, Juhua Li, Ximo Wang, Thomas E Ichim, Shi Chen, Gang Chen (通讯作者). Resistance of neonatal .porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of α-Gal and high production of clusterin and CD59. Xenotransplantation 2010;17:215-223(IF=2.067)
10.Zhuzeng Yin, Dong Chen,Feng Hu, Junhua Li, Lu Wang, Ying Xiang, Lin Xie, Thomas E Ichim, Shi Chen, Gang Chen (通讯作者). Cotransplantation with xenogenetic neonatal porcine Sertoli cells significantly prolongs islet allograft survival in non-immunosuppressive rats. Transplantation 2009;88(3):339-346 (IF=3.498)
11.Song Chen, Qing Wei, Junhua Li, Ying Xiang, Hui Guo, Thomas E Ichim, Shi Chen, Gang Chen (通讯作者). A simple and reliable method to Blood type monkeys using serum samples. Transplant International 2009;22(10):999-1004(IF=3.254)
12.Biao Feng, Gang Chen (共同第一作者及通讯作者), Xiufen Zheng, Hongtao Sun, Xusheng Zhang, Zhu-Xu Zhang, Ying Xiang, Thomas E Ichim, Bertha Garcia, Patrick Luke, Anthony M Jevnikar, Wei-Ping Min. Small interfering RNA targeting RelB protects against renal ischemia-reperfusion injury. Transplantation 2009;87:1283-1289 (IF=3.498)
13.Zhu L, Lin Z, Xiang Y, Liu S, Chen G(通讯作者). Successful desensitization in a crossmatch positive living-related kidney transplant recipient using a bortezomib-based protocol. Clin Transpl. 2009:359-60.(IF=2.004)
14.Zhu M, Zhang W, Liu F, Wang L, Liu B, Chen D, Zhu XH, Zhang WJ, Ichim TE, Chen ZS, Zhou P, Chen S*, Chen G*(通讯作者). Resistance to anti-xenogeneic response by combining alpha-Gal silencing with HO-1 upregulation. Transpl Immunol. 2008;19:202-208 (IF=1.869)
15.Gong Q, Yin H, Fang M, Xiang Y, Yuan CL, Zheng GY, Yang H, Xiong P, Chen G* (共同通讯作者), Gong FL*, Zheng F. Heme oxygenase-1 upregulation significantly inhibits TNF-α and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in mice. International Immunopharmacology (2008) 8(6):792-798(IF=2.157)
16.Chen G, Luke p, Yang H, Visser L, Sun H, Garcia B, Qian A, Xiang Y, Huang X, Liu W, Senaldi G, Poppema S, Jevnikar AM, Zhong R. CD45RB monoclonal antibody prolongs renal allograft survival in cynomolgus monkeys. Am J Transplant 2007; 7:27-37.(IF=6.423)
17.Chen G, Sun H, ARP J, Garcia B, Wang X, Wise Y, Liu W, Ramcharran S, Huang X, Xiang Y, Yang H, Fang Z, Madenas J, Sudo Y, Tamura K, and Zhong R. A synergistic effect between PG490-88 and tacrolimus prolongs renal allograft survival in monkeys. Am J Transplant 2006;6:714-723.(IF=6.843)
18.Chen G, Sun HT, Yang H, Kubelik D, Garcia B, Luo Y, Xiang Y, Qian A, Copeman L, Liu W, Cardella CJ, Wang W, Xiong Y, Wall W, White DJ, and Zhong R. The role of anti-non-Gal antibodies in the development of acute humoral xenograft rejection of hDAF transgenic porcine kidneys inbaboons receiving anti-Gal antibody neutralization therapy. Transplantation 2006; 81(2): 273-283.(IF=3.972)
19.Chen G, Qian H, Starzl T, Sun H, Garcia B, Wang X, Wise Y, Liu Y, Xiang Y, Copeman L, Liu W, Jevnikar A, Wall W, Cooper DKC, Murase N, Dai Y, Wang W, Xiong Y, White DJ, and Zhong R. Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nature Medicine 2005; 11(12): 1295-1298. (IF=28.878)
20.Chen G, Sun QY, Wang XM, Shen SQ, Guo H, Wang H, Wu Y, Wang WY, Xiong YL, and Chen S. Improved suppression of circulating complement does not block acute vascular rejection of pig-to-rhesus monkey cardiac transplants. Xenotransplantation 2004; 11 (2): 123-132 (SCI IF=2.876)
21.Chen G, Wei Q, Wang XM, Wang WY, Xiong YL, and Chen S. TMVA, a novel GPIb-binding protein, significantly prevents platelet microthrombi formation and prolongs discordant cardiac xenograft survival. Xenotransplantation 2004; 11 (2): 203-209 (SCI IF=2.876)
22.Sun QY, Chen G (co-first author), Guo H, Chen S, Wang WY, Xiong YL. Prolonged cardiac xenograft survival in guinea pig-to-rat model by a highly active cobra venom factor. Toxicon 2003; 42 (3): 257-262(IF=2.02)